{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/sl\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 Vrednost IMPACT pri podpiranju znanstvenih raziskav: dve novi znanstveni publikaciji za IMPACT!"},"content":{"rendered":"

\ud83d\udce2 Ponosni smo, da lahko delimo dve nedavni znanstveni publikaciji z odprtim dostopom, do katerih Projekt IMPACT EU<\/a> je prispeval in podprl prelomne raziskave o aritmogeni kardiomiopatiji (ACM).<\/p>\n

\ud83d\udd2c Pregled \u201eNapredki pri modeliranju aritmogenih kardiomiopatij z uporabo modelov pluripotentnih mati\u010dnih celic, ki jih povzro\u010di \u010dlovek\u201c prou\u010duje najnovej\u0161i napredek pri razvoju modelov za ACM, ki temeljijo na hiPSC. Razpravljajo o 2D in 3D modelih, ki ka\u017eejo njihovo sposobnost posnemanja klju\u010dnih patolo\u0161kih zna\u010dilnosti in njihov potencial za odkrivanje mehanizmov in testiranje inovativnih terapij.<\/p>\n

\ud83d\udc49 Celoten \u010dlanek preberite tukaj: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a \u0160tudija \u201eGivinostat zavira in vitro diferenciacijo sr\u010dnih fibroadipogenih predhodnih sestavin iz mi\u0161jega modela aritmogene kardiomiopatije\u201c, objavljena v publikaciji Biomedicine & Pharmacotherapy, ka\u017ee, kako lahko zdravilo Givinostat \u2013 zaviralec histonske deacetilaze, ki je \u017ee odobren za druge bolezni \u2013 zmanj\u0161a proliferacijo in diferenciacijo sr\u010dnih fibroadipogenih predhodnih sestavin (cFAPs), tj. celic, ki so odgovorne za nadome\u0161\u010danje fibroma\u0161\u010dob, zna\u010dilno za ACM. Te ugotovitve odpirajo obetavne mo\u017enosti za prihodnje ciljno usmerjene terapije.<\/p>\n

\ud83d\udc49 Celoten \u010dlanek preberite tukaj: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d Ti \u010dlanki predstavljajo oprijemljive rezultate, ki jih Projekt IMPACT EU<\/a> Prina\u0161a v ACM raziskave, \u0161iri znanje in odpira nove terapevtske perspektive!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Univerzitetni klini\u010dni center Leiden<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Ponosni smo, da lahko delimo dve nedavni znanstveni publikaciji z odprtim dostopom, h katerima je prispeval projekt IMPACT EU, ki podpirata prelomne raziskave na podro\u010dju aritmogene kardiomiopatije (ACM). \ud83d\udd2c Pregled \u201eNapredki pri modeliranju aritmogenih kardiomiopatij z uporabo modelov pluripotentnih mati\u010dnih celic, ki jih povzro\u010di \u010dlovek\u201c prou\u010duje najnovej\u0161i napredek pri razvoju modelov za ACM, ki temeljijo na hiPSC. 2D in 3D modeli\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/sl\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}