{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/ro\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 Valoarea IMPACT \u00een sprijinirea cercet\u0103rii \u0219tiin\u021bifice: dou\u0103 noi publica\u021bii \u0219tiin\u021bifice pentru IMPACT!"},"content":{"rendered":"

\ud83d\udce2 Suntem m\u00e2ndri s\u0103 \u00eemp\u0103rt\u0103\u0219im dou\u0103 publica\u021bii \u0219tiin\u021bifice recente cu acces liber la care Proiectul IMPACT EU<\/a> a contribuit, sprijinind cercetarea revolu\u021bionar\u0103 privind cardiomiopatia aritmogenic\u0103 (ACM).<\/p>\n

\ud83d\udd2c The review \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d (Avansuri \u00een modelarea cardiomiopatiei aritmogene utiliz\u00e2nd modele bazate pe celule stem pluripotente induse de om) exploreaz\u0103 cele mai recente progrese \u00een dezvoltarea de modele bazate pe hiPSC pentru ACM. Sunt discutate at\u00e2t modelele 2D, c\u00e2t \u0219i cele 3D, care demonstreaz\u0103 capacitatea lor de a reproduce caracteristici patologice cheie \u0219i poten\u021bialul lor de a descoperi mecanisme \u0219i de a testa terapii inovatoare.<\/p>\n

\ud83d\udc49 Citi\u021bi articolul integral aici: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a Studiul \u201eGivinostat inhib\u0103 diferen\u021bierea in vitro a precursorilor fibroadipogenici cardiaci fa\u021b\u0103 de un model de cardiomiopatie aritmogenic\u0103 la \u0219oarece\u201d, publicat \u00een Biomedicine & Pharmacotherapy, arat\u0103 modul \u00een care medicamentul Givinostat \u2013 un inhibitor de histon\u0103 deacetilaz\u0103 deja aprobat pentru alte afec\u021biuni \u2013 poate reduce proliferarea \u0219i diferen\u021bierea precursorilor fibroadipogenici cardiaci (cFAP), celulele responsabile pentru \u00eenlocuirea fibrogras\u0103 tipic\u0103 a ACM. Aceste descoperiri deschid c\u0103i promi\u021b\u0103toare pentru viitoarele terapii \u021bintite.<\/p>\n

\ud83d\udc49 Citi\u021bi articolul integral aici: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d Aceste articole reprezint\u0103 rezultatele tangibile pe care Proiectul IMPACT EU<\/a> aduce la cercetarea ACM, extinderea cuno\u0219tin\u021belor \u0219i deschiderea de noi perspective terapeutice!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Centrul Medical Universitar din Leiden<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Suntem m\u00e2ndri s\u0103 \u00eemp\u0103rt\u0103\u0219im dou\u0103 publica\u021bii \u0219tiin\u021bifice recente cu acces liber la care a contribuit proiectul IMPACT EU, sprijinind cercetarea inovatoare privind cardiomiopatia aritmogenic\u0103 (ACM). \ud83d\udd2c The review \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d (Avansuri \u00een modelarea cardiomiopatiei aritmogene utiliz\u00e2nd modele bazate pe celule stem pluripotente induse de om) exploreaz\u0103 cele mai recente progrese \u00een dezvoltarea de modele bazate pe hiPSC pentru ACM. Ambele modele 2D \u0219i 3D\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/ro\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}