{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/pl\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 Warto\u015b\u0107 IMPACT we wspieraniu bada\u0144 naukowych: Dwie nowe publikacje naukowe dla IMPACT!"},"content":{"rendered":"

\ud83d\udce2 Z dum\u0105 dzielimy si\u0119 dwiema najnowszymi publikacjami naukowymi o otwartym dost\u0119pie, do kt\u00f3rych Projekt IMPACT EU<\/a> przyczyni\u0142 si\u0119, wspieraj\u0105c prze\u0142omowe badania nad kardiomiopati\u0105 arytmogenn\u0105 (ACM).<\/p>\n

\ud83d\udd2c Przegl\u0105d \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d bada najnowsze post\u0119py w opracowywaniu modeli ACM opartych na hiPSC. Om\u00f3wiono zar\u00f3wno modele 2D, jak i 3D, pokazuj\u0105c ich zdolno\u015b\u0107 do powielania kluczowych cech patologicznych i ich potencja\u0142 do odkrywania mechanizm\u00f3w i testowania innowacyjnych terapii.<\/p>\n

\ud83d\udc49 Przeczytaj ca\u0142y artyku\u0142 tutaj: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a Badanie \u201eGivinostat inhibits in vitro differentiation of cardiac fibroadipogenic precursors from a mouse model of arrhythmogenic cardiomyopathy\u201d, opublikowane w Biomedicine & Pharmacotherapy, pokazuje, w jaki spos\u00f3b lek Givinostat \u2013 inhibitor deacetylazy histonowej ju\u017c zatwierdzony do stosowania w innych schorzeniach \u2013 mo\u017ce zmniejsza\u0107 proliferacj\u0119 i r\u00f3\u017cnicowanie prekursor\u00f3w fibroadipogennych sercowych (cFAP), kom\u00f3rek odpowiedzialnych za za zast\u0105pienie t\u0142uszczu w\u0142\u00f3knistego typowe dla ACM. Odkrycia te otwieraj\u0105 obiecuj\u0105ce drogi dla przysz\u0142ych terapii ukierunkowanych.<\/p>\n

\ud83d\udc49 Przeczytaj ca\u0142y artyku\u0142 tutaj: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d Artyku\u0142y te przedstawiaj\u0105 wymierne rezultaty, kt\u00f3re Projekt IMPACT EU<\/a> Wnosi do bada\u0144 ACM, poszerza wiedz\u0119 i otwiera nowe perspektywy terapeutyczne!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Centrum Medyczne Uniwersytetu w Lejdzie<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Z dum\u0105 dzielimy si\u0119 dwiema niedawnymi publikacjami naukowymi o otwartym dost\u0119pie, do kt\u00f3rych przyczyni\u0142 si\u0119 projekt IMPACT EU, wspieraj\u0105c prze\u0142omowe badania nad kardiomiopati\u0105 arytmogenn\u0105 (ACM). \ud83d\udd2c Przegl\u0105d \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d bada najnowsze post\u0119py w opracowywaniu modeli ACM opartych na hiPSC. Zar\u00f3wno modele 2D, jak i 3D\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/pl\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}