{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/lt\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 IMPACT reik\u0161m\u0117 remiant mokslinius tyrimus: du nauji IMPACT moksliniai leidiniai!"},"content":{"rendered":"

\ud83d\udce2 Mes did\u017eiuojam\u0117s gal\u0117dami pasidalinti dviem naujausiais atviros prieigos moksliniais leidiniais, su kuriais Projektas \u201eIMPACT EU\u201c<\/a> prisid\u0117jo prie novatori\u0161k\u0173 aritmogenin\u0117s kardiomiopatijos (AKM) mokslini\u0173 tyrim\u0173 r\u0117mimo.<\/p>\n

\ud83d\udd2c Ap\u017evalgoje \u201eAdvances in arhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell based models\u201c nagrin\u0117jama naujausia pa\u017eanga kuriant hiPSC pagr\u012fstus ACM modelius. Aptariami tiek 2D, tiek 3D modeliai, parodantys j\u0173 geb\u0117jim\u0105 atkartoti pagrindinius patologinius bruo\u017eus ir j\u0173 potencial\u0105 atskleisti mechanizmus ir i\u0161bandyti naujovi\u0161kus gydymo b\u016bdus.<\/p>\n

\ud83d\udc49 Vis\u0105 straipsn\u012f skaitykite \u010dia: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a Tyrimas \u201eGivinostatas slopina \u0161irdies fibroadipogenini\u0173 pirmtak\u0173 diferencijavim\u0105 in vitro nuo peli\u0173 aritmogenin\u0117s kardiomiopatijos modelio\u201c, paskelbtas leidinyje \u201eBiomedicine & Pharmacotherapy\u201c, rodo, kaip vaistas Givinostat \u2013 kitomis s\u0105lygomis jau patvirtintas histone deacetilaz\u0117s inhibitorius \u2013 gali suma\u017einti \u0161irdies fibroadipogenini\u0173 pirmtak\u0173 (cFAP), t. y. l\u0105steli\u0173, atsaking\u0173 u\u017e ACM b\u016bding\u0105 fibroriebal\u0173 pakeitim\u0105, proliferacij\u0105 ir diferenciacij\u0105. \u0160ios i\u0161vados atveria perspektyvias galimybes b\u016bsimiems tiksliniams gydymo b\u016bdams.<\/p>\n

\ud83d\udc49 Vis\u0105 straipsn\u012f skaitykite \u010dia: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d \u0160ie straipsniai atspindi ap\u010diuopiamus rezultatus, kad Projektas \u201eIMPACT EU\u201c<\/a> Atne\u0161a \u012f ACM mokslinius tyrimus, ple\u010dia \u017einias ir atveria naujas terapines perspektyvas!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Leideno universiteto medicinos centras<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Mes did\u017eiuojam\u0117s gal\u0117dami pasidalinti dviem naujausiais atviros prieigos moksliniais leidiniais, prie kuri\u0173 prisid\u0117jo IMPACT EU projektas, remdamas novatori\u0161kus aritmogenin\u0117s kardiomiopatijos (ACM) mokslinius tyrimus. \ud83d\udd2c Ap\u017evalgoje \u201eAdvances in arhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell based models\u201c nagrin\u0117jama naujausia pa\u017eanga kuriant hiPSC pagr\u012fstus ACM modelius. Ir 2D, ir 3D modeliai\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/lt\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}