{"id":1689,"date":"2020-03-25T10:38:51","date_gmt":"2020-03-25T10:38:51","guid":{"rendered":"http:\/\/novalab.bold-themes.com\/main-demo\/?page_id=1689"},"modified":"2026-03-09T11:12:31","modified_gmt":"2026-03-09T10:12:31","slug":"home","status":"publish","type":"page","link":"https:\/\/impact-acmproject.eu\/lt\/","title":{"rendered":"Pagrindinis puslapis"},"content":{"rendered":"

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\"https:\/\/impact-acmproject.eu\/wp-content\/uploads\/2023\/11\/logo_titolo.webp\"<\/span><\/div><\/div><\/div><\/div>
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Kardiogenomika ir dirbtinis intelektas: \u017eingsnis \u012f priek\u012f aritmogenin\u0117s kardiomiopatijos diagnozavimo ir gydymo srityje<\/span><\/span><\/h1><\/header>

Kardiogenomika ir dirbtinis intelektas: \u017eingsnis \u012f priek\u012f aritmogenin\u0117s kardiomiopatijos diagnozavimo ir gydymo srityje<\/span><\/span><\/h1><\/header>
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Apie projekt\u0105<\/span><\/span><\/a><\/div>
NAUJIENOS IR RENGINIAI<\/span><\/span><\/a><\/div>
Publikacijos<\/span><\/span><\/a><\/div>
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Apie projekt\u0105<\/span><\/span><\/div>
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Aritmogenin\u0117 kardiomiopatija (ACM) yra genetin\u0117 liga, kuri gali sukelti skilveli\u0173 aritmijas ir staigi\u0105 \u0161irdies mirt\u012f (SCD), ypa\u010d jauniems ir sportininkams. ACM b\u016bdingas progresuojantis kardiomiocit\u0173 praradimas ir fibroriebumo pakeitimas.<\/p>\n

\u0160iuo metu n\u0117ra veiksming\u0173 ACM gydymo b\u016bd\u0173. Taigi, jos valdymas orientuotas \u012f SCD prevencij\u0105 ir ligos progresavimo sul\u0117tinim\u0105.<\/p>\n

Bendras projekto tikslas - sujungti didelio masto -omikos duomenis, gautus i\u0161 pacient\u0173, su strukt\u016brin\u0117s ir funkcin\u0117s analiz\u0117s duomenimis. in vitro<\/em> ir in vivo<\/em> modeliai, siekiant nustatyti genotipo ir \u0161irdies fenotipo ry\u0161ius.<\/p>\n

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\u0160iuo tikslu IMPACT \u012fgyvendins dirbtiniu intelektu (DI) pagr\u012fst\u0105 klinikini\u0173 ir -omikos duomen\u0173 i\u0161 ACM pacient\u0173 registro integravim\u0105, naudodamas nepri\u017ei\u016brim\u0105 mi\u0161ri\u0173 duomen\u0173 grupavim\u0105 ir fenotip\u0173 nustatym\u0105, kad b\u016bt\u0173 galima nustatyti fenotipo pogrupius pacient\u0173 kohortoje, kad b\u016bt\u0173 galima nustatyti terapiniu b\u016bdu veikiamus tikslus ir stratifikuoti ACM sergan\u010dius pacientus. Projektas sukurs ir apib\u016bdins atitinkamus ikiklinikinius modelius, b\u016btent 3D in vitro <\/em>\u0161irdies mikrotissues; ji taip pat nustatys j\u0173 naudingum\u0105 ai\u0161kinant \u0161i\u0173 ligos gen\u0173 atmainas, kurios yra neai\u0161kios klinikin\u0117s reik\u0161m\u0117s, ir nustatant patologinius molekulinius kelius, kurie gali b\u016bti taikomi terapiniu po\u017ei\u016briu.<\/p>\n

Savo darbu projektu siekiama paruo\u0161ti dirv\u0105 naujiems pagrindini\u0173 \u0161irdies ir kraujagysli\u0173 lig\u0173 gydymo b\u016bdams.<\/p>\n

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Projekto partneris<\/span><\/span><\/div>
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\"Universit\u00e0<\/a><\/div><\/div><\/div><\/div>
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\"Mastrichto<\/a><\/div><\/div><\/div><\/div>
\"AccelBio\"<\/a><\/div><\/div><\/div><\/div><\/div><\/div>
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Naujienos ir renginiai<\/span><\/span><\/h2><\/header>
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\r\n\t\t<\/div>
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