{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/hu\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 Az IMPACT \u00e9rt\u00e9ke a tudom\u00e1nyos kutat\u00e1s t\u00e1mogat\u00e1s\u00e1ban: K\u00e9t \u00faj tudom\u00e1nyos publik\u00e1ci\u00f3 az IMPACT sz\u00e1m\u00e1ra!"},"content":{"rendered":"

\ud83d\udce2 B\u00fcszk\u00e9k vagyunk arra, hogy megoszthatunk k\u00e9t friss, ny\u00edlt hozz\u00e1f\u00e9r\u00e9s\u0171 tudom\u00e1nyos publik\u00e1ci\u00f3t, amelyekhez IMPACT EU-projekt<\/a> hozz\u00e1j\u00e1rult, t\u00e1mogatva az aritmog\u00e9n kardiomiop\u00e1tia (ACM) \u00fatt\u00f6r\u0151 kutat\u00e1s\u00e1t.<\/p>\n

\ud83d\udd2c Az \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d (El\u0151rel\u00e9p\u00e9sek az aritmog\u00e9n kardiomiop\u00e1tia modellez\u00e9s\u00e9ben ember \u00e1ltal induk\u00e1lt pluripotens \u0151ssejt-alap\u00fa modellek felhaszn\u00e1l\u00e1s\u00e1val) c\u00edm\u0171 \u00e1ttekint\u00e9s az ACM hiPSC-alap\u00fa modelljeinek kifejleszt\u00e9se ter\u00e9n el\u00e9rt leg\u00fajabb eredm\u00e9nyeket vizsg\u00e1lja. Mind a 2D-s, mind a 3D-s modelleket megvitatj\u00e1k, bemutatva, hogy k\u00e9pesek-e megism\u00e9telni a kulcsfontoss\u00e1g\u00fa patol\u00f3giai jellemz\u0151ket, \u00e9s k\u00e9pesek-e felt\u00e1rni a mechanizmusokat \u00e9s tesztelni az innovat\u00edv ter\u00e1pi\u00e1kat.<\/p>\n

\ud83d\udc49 A teljes cikk itt olvashat\u00f3: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/teljes sz\u00f6veg<\/p>\n

\ud83d\udc8a A Biomedicine & Pharmacotherapy foly\u00f3iratban k\u00f6zz\u00e9tett, \u201eGivinostat inhibits in vitro differentiation of cardiac fibroadipogenic precursors from a mouse model of arrhythmogenic cardiomyopathy\u201d (A givinosztat g\u00e1tolja a sz\u00edvfibroadipog\u00e9n prekurzorok in vitro megk\u00fcl\u00f6nb\u00f6ztet\u00e9s\u00e9t az arrhythmogenic cardiomyopathia eg\u00e9rmodellj\u00e9t\u0151l; Farmakoter\u00e1pia) c\u00edm\u0171 tanulm\u00e1ny bemutatja, hogy a Givinostat gy\u00f3gyszer \u2013 egy m\u00e1s betegs\u00e9gekre m\u00e1r j\u00f3v\u00e1hagyott hiszton-deacetil\u00e1z inhibitor \u2013 hogyan cs\u00f6kkentheti a sz\u00edvfibroadipogen prekurzorok (cFAPs) prolifer\u00e1ci\u00f3j\u00e1t \u00e9s differenci\u00e1l\u00f3d\u00e1s\u00e1t, amelyek az ACM-re jellemz\u0151 fibrozs\u00edrp\u00f3tl\u00e1s\u00e9rt felel\u0151s sejtek. Ezek az eredm\u00e9nyek \u00edg\u00e9retes utakat nyitnak meg a j\u00f6v\u0151beli c\u00e9lzott ter\u00e1pi\u00e1k el\u0151tt.<\/p>\n

\ud83d\udc49 A teljes cikk itt olvashat\u00f3: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d Ezek a cikkek azokat a k\u00e9zzelfoghat\u00f3 eredm\u00e9nyeket k\u00e9pviselik, amelyeket a IMPACT EU-projekt<\/a> az ACM kutat\u00e1shoz, a tud\u00e1s b\u0151v\u00edt\u00e9s\u00e9hez \u00e9s \u00faj ter\u00e1pi\u00e1s perspekt\u00edv\u00e1k megnyit\u00e1s\u00e1hoz vezet!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Leideni Egyetemi Orvosi K\u00f6zpont<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 B\u00fcszk\u00e9k vagyunk arra, hogy megoszthatunk k\u00e9t friss, ny\u00edlt hozz\u00e1f\u00e9r\u00e9s\u0171 tudom\u00e1nyos publik\u00e1ci\u00f3t, amelyekhez az IMPACT EU projekt hozz\u00e1j\u00e1rult, t\u00e1mogatva az arrhythmogenic cardiomyopathi\u00e1val (ACM) kapcsolatos \u00fatt\u00f6r\u0151 kutat\u00e1sokat. \ud83d\udd2c Az \u201eAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d (El\u0151rel\u00e9p\u00e9sek az aritmog\u00e9n kardiomiop\u00e1tia modellez\u00e9s\u00e9ben ember \u00e1ltal induk\u00e1lt pluripotens \u0151ssejt-alap\u00fa modellek felhaszn\u00e1l\u00e1s\u00e1val) c\u00edm\u0171 \u00e1ttekint\u00e9s az ACM hiPSC-alap\u00fa modelljeinek kifejleszt\u00e9se ter\u00e9n el\u00e9rt leg\u00fajabb eredm\u00e9nyeket vizsg\u00e1lja. 2D \u00e9s 3D modellek \u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/hu\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}