{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/fi\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 IMPACTin arvo tieteellisen tutkimuksen tukemisessa: kaksi uutta tieteellist\u00e4 julkaisua IMPACTille!"},"content":{"rendered":"

\ud83d\udce2 Olemme ylpeit\u00e4 voidessamme jakaa kaksi tuoretta avointa tieteellist\u00e4 julkaisua, joihin IMPACT EU -hanke<\/a> on tukenut uraauurtavaa rytmih\u00e4iri\u00f6it\u00e4 aiheuttavaa kardiomyopatiaa (ACM) koskevaa tutkimusta.<\/p>\n

\ud83d\udd2c Katsauksessa \u201dAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d tarkastellaan viimeisint\u00e4 edistymist\u00e4 hiPSC-pohjaisten mallien kehitt\u00e4misess\u00e4 ACM:\u00e4\u00e4 varten. Sek\u00e4 2D- ett\u00e4 3D-malleja k\u00e4sitell\u00e4\u00e4n, mik\u00e4 osoittaa niiden kyvyn toistaa keskeisi\u00e4 patologisia piirteit\u00e4 ja niiden mahdollisuuden paljastaa mekanismeja ja testata innovatiivisia hoitoja.<\/p>\n

\ud83d\udc49 Lue koko artikkeli t\u00e4\u00e4lt\u00e4: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a Biomedicine & Pharmacotherapy -lehdess\u00e4 julkaistu tutkimus \u201dGivinostat inhibits in vitro differentiation of cardiac fibroadipogenic precursors from a mouse model of arrhythmogenic cardiomyopathy\u201d osoittaa, miten l\u00e4\u00e4ke Givinostat \u2013 histone deacetylase inhibitor, joka on jo hyv\u00e4ksytty muihin sairauksiin \u2013 voi v\u00e4hent\u00e4\u00e4 syd\u00e4men fibroadipogenic precursors (cFAPs) -solujen proliferaatiota ja erilaistumista. N\u00e4m\u00e4 havainnot avaavat lupaavia v\u00e4yli\u00e4 tuleville kohdennetuille hoidoille.<\/p>\n

\ud83d\udc49 Lue koko artikkeli t\u00e4\u00e4lt\u00e4: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d N\u00e4m\u00e4 artikkelit edustavat konkreettisia tuloksia, joita IMPACT EU -hanke<\/a> tuo ACM-tutkimukseen, laajentaa tietoa ja avaa uusia terapeuttisia n\u00e4k\u00f6kulmia!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Leidenin yliopiston l\u00e4\u00e4ketieteellinen keskus<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, Monica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Olemme ylpeit\u00e4 voidessamme jakaa kaksi \u00e4skett\u00e4ist\u00e4 avointa tieteellist\u00e4 julkaisua, joihin IMPACT EU -hanke on osallistunut ja jotka tukevat uraauurtavaa tutkimusta rytmih\u00e4iri\u00f6iden kardiomyopatiasta (ACM). \ud83d\udd2c Katsauksessa \u201dAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u201d tarkastellaan viimeisint\u00e4 edistymist\u00e4 hiPSC-pohjaisten mallien kehitt\u00e4misess\u00e4 ACM:\u00e4\u00e4 varten. Sek\u00e4 2D- ett\u00e4 3D-mallit\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/fi\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}