{"id":3940,"date":"2025-09-26T17:56:40","date_gmt":"2025-09-26T15:56:40","guid":{"rendered":"https:\/\/impact-acmproject.eu\/?p=3940"},"modified":"2025-09-26T17:56:40","modified_gmt":"2025-09-26T15:56:40","slug":"%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact","status":"publish","type":"post","link":"https:\/\/impact-acmproject.eu\/es\/%f0%9f%ab%80-the-value-of-impact-in-supporting-scientific-research-two-new-scientific-publications-for-impact\/","title":{"rendered":"\ud83e\udec0 El valor de IMPACT en el apoyo a la investigaci\u00f3n cient\u00edfica: dos nuevas publicaciones cient\u00edficas para IMPACT!"},"content":{"rendered":"

\ud83d\udce2 Estamos orgullosos de compartir dos publicaciones cient\u00edficas recientes de acceso abierto a las cuales Proyecto IMPACT EU<\/a> ha contribuido, apoyando la investigaci\u00f3n innovadora sobre la miocardiopat\u00eda arritmog\u00e9nica (ACM).<\/p>\n

\ud83d\udd2c La revisi\u00f3n \u00abAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u00bb explora los \u00faltimos avances en el desarrollo de modelos basados en hiPSC para ACM. Se discuten los modelos 2D y 3D, mostrando su capacidad para replicar caracter\u00edsticas patol\u00f3gicas clave y su potencial para descubrir mecanismos y probar terapias innovadoras.<\/p>\n

\ud83d\udc49 Lea el art\u00edculo completo aqu\u00ed: https:\/\/www.heartrhythmjournal.com\/article\/S1547-5271(25)02753-5\/fulltext<\/p>\n

\ud83d\udc8a El estudio \u00abGivinostat inhibe la diferenciaci\u00f3n in vitro de precursores fibroadipog\u00e9nicos card\u00edacos a partir de un modelo de miocardiopat\u00eda arritmog\u00e9nica en ratones\u00bb, publicado en Biomedicine & Pharmacotherapy, muestra c\u00f3mo el medicamento Givinostat, un inhibidor de la histona deacetilasa ya aprobado para otras afecciones, puede reducir la proliferaci\u00f3n y la diferenciaci\u00f3n de precursores fibroadipog\u00e9nicos card\u00edacos (cFAP), las c\u00e9lulas responsables del reemplazo fibrograso t\u00edpico de la MCA. Estos hallazgos abren v\u00edas prometedoras para futuras terapias dirigidas.<\/p>\n

\ud83d\udc49 Lea el art\u00edculo completo aqu\u00ed: https:\/\/doi.org\/10.1016\/j.biopha.2025.118549<\/p>\n

\ud83c\udf0d Estos art\u00edculos representan los resultados tangibles que el Proyecto IMPACT EU<\/a> \u00a1Est\u00e1 aportando a la investigaci\u00f3n de ACM, expandiendo el conocimiento y abriendo nuevas perspectivas terap\u00e9uticas!<\/p>\n

Universit\u00e0 degli Studi di Padova<\/a>, Centro M\u00e9dico de la Universidad de Leiden<\/a>, Italfarmaco<\/a><\/p>\n

Alessandra Rampazzo<\/a>, Martina Calore<\/a>, Sara Vencato<\/a>, Chiara Romanato<\/a>, Angelo Velle<\/a>, Nicola Facchinello<\/a>, Paola Braghetta<\/a>, Chiara Romualdi<\/a>, Libero Vitiello<\/a>, Simonetta Andrea Licandro<\/a>, Christian Steinkuhler<\/a>, M\u00f3nica Forino<\/a>, Gianluca Fossati<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\ud83d\udce2 Estamos orgullosos de compartir dos publicaciones cient\u00edficas recientes de acceso abierto a las que el proyecto IMPACT EU ha contribuido, apoyando la investigaci\u00f3n innovadora sobre la miocardiopat\u00eda arritmog\u00e9nica (ACM). \ud83d\udd2c La revisi\u00f3n \u00abAdvances in arrhythmogenic cardiomyopathy modeling using human-induced pluripotent stem cell-based models\u00bb explora los \u00faltimos avances en el desarrollo de modelos basados en hiPSC para ACM. 2D y 3D \u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3940","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/posts\/3940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/comments?post=3940"}],"version-history":[{"count":1,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/posts\/3940\/revisions"}],"predecessor-version":[{"id":3941,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/posts\/3940\/revisions\/3941"}],"wp:attachment":[{"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/media?parent=3940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/categories?post=3940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-acmproject.eu\/es\/wp-json\/wp\/v2\/tags?post=3940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}