The IMPACT project has officially started! With 7 Partners from different EU countries 🇪🇺 , IMPACT will implement an Artificial Intelligence (AI)-based integration of clinical and -omics data from ACM patient registry utilizing unsupervised mixed-data clustering and phenomapping to identify phenotypic subgroups within the cohort of patients leading to the detection of therapeutically actionable targets as well as to stratify ACM patients.
The project will develop and characterize relevant preclinical models, namely 3D in vitro cardiac microtissues; it will also establish their utility in the interpretation of variants in these disease genes that are of uncertain clinical significance and in the identification of pathological molecular pathways that can be therapeutically targeted.
With its work IMPACT intends to pave the way for novel therapies for major cardiovascular diseases conditions.
Stay tuned and follow us for more news on IMPACT upcoming results!
